Clinical Research and Trials
Advancing Retina Care Through Clinical Research
At Retina Consultants of Southern California, providing outstanding retina care means not only using today’s most advanced treatments, but also helping develop the treatments of tomorrow.
RCSC has a long-standing commitment to clinical research and has participated in more than 70 clinical trials evaluating innovative therapies for retinal diseases. Our physicians have served as investigators in studies ranging from early-phase research to large, multicenter Phase 3 clinical trials conducted in collaboration with many of the world’s leading pharmaceutical and biotechnology companies.
Our research experience spans many of the conditions we treat every day, including wet age-related macular degeneration (AMD), geographic atrophy, diabetic macular edema, diabetic retinopathy, retinal vein occlusion, and inflammatory retinal disease.
Over the years, RCSC has helped investigate a broad range of emerging treatments, including new anti-VEGF medications, extended-duration therapies, complement inhibitors, eye drops, oral medications, suprachoroidal treatments, sustained-release therapies, and, more recently, ocular gene therapy.
A Leading Retina Research Center in Southern CA
Clinical research has been an important part of our practice for more than a decade. Our physicians and experienced research team have worked with leading pharmaceutical and biotechnology companies on studies that have helped evaluate both established treatments and the next generation of retinal therapies.
Today, RCSC continues to participate in multiple national and international clinical trials, including studies of investigational treatments designed to improve vision, extend the duration of treatment, reduce the number of injections patients require, and treat retinal diseases in entirely new ways.
For eligible patients, participation in a clinical trial may provide access to promising investigational therapies before they become commercially available. Every study is conducted under a carefully designed research protocol with extensive attention to patient safety, informed consent, and appropriate clinical oversight.
An Experienced Research Team
Successful clinical research requires much more than access to new medications. It requires experienced physicians, dedicated research coordinators, sophisticated retinal imaging, careful patient monitoring, and the ability to follow complex clinical trial protocols over months or even years.
RCSC has developed this infrastructure through years of participation in clinical research. Our dedicated research team works closely with our physicians, study sponsors, and patients throughout every stage of a clinical trial.
We are proud that our patients in the Inland Empire and Southern California can participate in important retinal research close to home, while continuing to receive care from physicians they know and trust.
Explore Our Research
View our Current Clinical Trials to see studies that are actively enrolling or currently underway, or explore our Past Clinical Trials to learn more about RCSC's history of participation in retinal research. If you would like to participate in our research program please contact our Research Coordinator, Jacque Smith, at (909) 335-8938 or jsmith@vrsurgeons.com.
Our Clinical Research Team
Our clinical research program is led by Jacque Smith, CRC, an experienced Certified Clinical Research Coordinator who has worked alongside our physicians on numerous Phase 1–3 retinal clinical trials since 2012.
Jacque oversees study coordination, patient screening and enrollment, regulatory requirements, and ongoing communication with study sponsors. Together with our physicians and research staff, she helps ensure that every clinical trial at RCSC is conducted with careful attention to patient safety, protocol compliance, and the highest standards of clinical research.
For patients considering a clinical trial, Jacque and our research team are available to explain the study, answer questions, and guide participants through every step of the process.

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